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SYNPO2L Antibody

SYNPO2L Antibody

Item no.	PRS-6053-0.1mg
Manufacturer	ProSci
Amount	0.1 mg
Category	Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, ELISA
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SYNPO2L Antibody: Synaptopodin 2-like protein
Available
Shipping	blue ice or RT
By Research Area	Signal Transduction
Immunogen	SYNPO2L antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SYNPO2L. The immunogen is located within amino acids 140 - 190 of SYNPO2L.
Applications	SYNPO2L antibody can be used for detection of SYNPO2L by Western blot at 1 μ g/mL. For immunofluorescence start at 20 μ g/mL. Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Positive Control 1	Cat. No. 1314 - Human Thymus Tissue Lysate
Purification	SYNPO2L Antibody is affinity chromatography purified via peptide column.
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	SYNPO2L Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/mL
Storage Conditions	SYNPO2L antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Related Products	Cat. No. 6053P – SYNPO2L Peptide
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	SYNPO2L
Accession #	BAD37139
Protein Gi #	51534920
Ncbi Gene Id #	79933
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	SYNPO2L
Ncbi Official Full Name	synaptopodin 2-like
Ncbi Organism	Homo sapiens
Swissprot #	Q9H987
Background	SYNPO2L Antibody: SYNPO2L was initially identified as a novel heart-enriched gene that encodes a cytoskeletal protein highly expressed in the Z-disc of heart and skeletal muscle, associates with actin and interacts with a-actinin. It is a member of the synaptopodin family, sharing greatest homology with Synaptopodin 2. Recent studies have shown that SYNPO2L, while primarily localized to the sarcomere, can also translocate to the nucleus. A knockdown of SYNPO2L in zebrafish resulted in aberrant cardiac and skeletal muscle development and function, suggesting that it is a critical component of the sarcomere and plays an important role in muscle development.
Background References 1	Beqqali A, Kloots J, Ward-van Oostward D, et al. Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes. Stem Cells2006; 24:1956-67.
Background References 2	Beqqali A, Manshouwer-Kloots J, Moneiro R, et al. CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function. J. Cell Sci.2010; 123:1141-50.
1st Image Caption	Western blot analysis of SYNPO2L in human thymus tissue lysate with SYNPO2L antibody at 1 μ g/mL in (A) the absence and (B) the presence of blocking peptide.
3rd Image Caption	Immunofluorescence of SYNPO2L in mouse skeletal muscle tissue with SYNPO2L antibody at 20 μ g/mL.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/6/2024

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