Item no. |
PRS-60-920-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Vesicle-fusing ATPase, N-ethylmaleimide-sensitive fusion protein, NEM-sensitive fusion protein, Vesicular-fusion protein NSF, NSF |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Neuroscience, Signal Transduction |
Homology |
Predicted species reactivity based on immunogen sequence: Hamster, Rat |
Immunogen |
This NSF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-696 amino acids from the C-terminal region of human NSF. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
83 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
NSF |
Accession # |
P46459 |
Protein Gi # |
257051048 |
Ncbi Gene Id # |
4905 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
NSF |
Ncbi Official Full Name |
Vesicle-fusing ATPase |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P46459 |
Background |
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seem to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin. |
Background References 1 |
Saus, E., et al.Psychiatr Res 44(14):971-978(2010) |
Background References 2 |
Hamza, T.H., et al. Nat. Genet. 42(9):781-785(2010) |
Background References 3 |
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) : |
Background References 4 |
Parashuraman, S., et al. FEBS Lett. 584(6):1251-1256(2010) |
1st Image Caption |
Western Blot at 1:1000 dilution Lane 1: Hela whole cell lysate Lane 2: SH-SY5Y whole cell lysate Lysates/proteins at 20 ug per lane. |
2nd Image Caption |
Western blot analysis in mouse cerebellum tissue lysates (35ug/lane). |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.