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TFEC Antibody

TFEC Antibody

Item no.	PRS-60-561-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Antibodies By Cell Type Carcinoma Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Transcription factor EC, TFE-C, Class E basic helix-loop-helix protein 34, bHLHe34, Transcription factor EC-like, hTFEC-L, TFEC, BHLHE34, TCFEC, TFECL
Available
Shipping	blue ice or RT
Homology	Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
Immunogen	This TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC.
Applications	For WB starting dilution is: 1:1000
Predicted Molecular Weight	39 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	TFEC
Accession #	O14948
Ncbi Gene Id #	22797
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	TFEC
Ncbi Official Full Name	Transcription factor EC
Ncbi Organism	Homo sapiens
Swissprot #	O14948
Background	Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo-or heterodimeric form.
Background References 1	Mansky, K.C., et al. J. Leukoc. Biol. 71(2):304-310(2002)
Background References 2	Chung, M.C., et al. Biochemistry 40(30):8887-8897(2001)
Background References 3	Steingrimsson, E., et al. Development 125(23):4607-4616(1998)
Background References 4	Yasumoto, K., et al. Biochim. Biophys. Acta 1353(1):23-31(1997)
1st Image Caption	Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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