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PDLIM3 Antibody

PDLIM3 Antibody

Item no.	PRS-60-169-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody
Format	Liquid
Applications	WB
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PDZ and LIM domain protein 3, Actinin-associated LIM protein, Alpha-actinin-2-associated LIM protein, PDLIM3, ALP
Available
Shipping	blue ice or RT
By Research Area	Signal Transduction
Immunogen	This PDLIM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-355 amino acids from the C-terminal region of human PDLIM3.
Applications	For WB starting dilution is: 1:1000
Predicted Molecular Weight	39 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	PDLIM3
Accession #	Q53GG5
Protein Gi #	74740479
Ncbi Gene Id #	27295
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	PDLIM3
Ncbi Official Full Name	PDZ and LIM domain protein 3
Ncbi Organism	Homo sapiens
Swissprot #	Q53GG5
Background	The protein encoded by this gene contains a PDZ domain anda LIM domain, indicating that it may be involved in cytoskeletalassembly. In support of this, the encoded protein has been shown tobind the spectrin-like repeats of alpha-actinin-2 and to colocalizewith alpha-actinin-2 at the Z lines of skeletal muscle. This geneis found near a region of chromosome 4 that has been implicated infacioscapulohumeral muscular dystrophy, but this gene does notappear to be involved in the disease. Two transcript variantsencoding different isoforms have been found for this gene.
Background References 1	Hershberger, R.E., et al. Clin Transl Sci 1(1):21-26(2008)
Background References 2	Keira, Y., et al. Neurosci. Res. 57(4):513-521(2007)
Background References 3	Arola, A.M., et al. Mol. Genet. Metab. 90(4):435-440(2007)
Background References 4	Klaavuniemi, T., et al. J. Biol. Chem. 279(25):26402-26410(2004)
1st Image Caption	Western blot analysis in HL-60 cell line lysates (35ug/lane).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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