Item no. |
PRS-59-654-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Myosin-9, Cellular myosin heavy chain, type A, Myosin heavy chain 9, Myosin heavy chain, non-muscle IIa, Non-muscle myosin heavy chain A, NMMHC-A, Non-muscle myosin heavy chain IIa, NMMHC II-a, NMMHC-IIA, MYH9 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Signal Transduction |
Immunogen |
This MYH9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1840-1867 amino acids from the C-terminal region of human MYH9. |
Applications |
For WB starting dilution is: 1:2000 |
Predicted Molecular Weight |
227 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
MYH9 |
Accession # |
P35579 |
Protein Gi # |
6166599 |
Ncbi Gene Id # |
4627 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
MYH9 |
Ncbi Official Full Name |
Myosin-9 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P35579 |
Background |
This gene encodes a myosin IIA heavy chain that containsan IQ domain and a myosin head-like domain. The protein is involvedin several important functions, including cytokinesis, cellmotility and maintenance of cell shape. Defects in MYH9 are thecause of non-syndromic sensorineural deafness autosomal dominanttype 17, Epstein syndrome, Alport syndrome withmacrothrombocytopenia, Sebastian syndrome, Fechtner syndrome andmacrothrombocytopenia with progressive sensorineural deafness. |
Background References 1 |
Arii, J., et al. Nature 467(7317):859-862(2010) |
Background References 2 |
Genovese, G., et al. Kidney Int. 78(7):698-704(2010) |
Background References 3 |
Tzur, S., et al. Hum. Genet. 128(3):345-350(2010) |
Background References 4 |
Bostrom, M.A., et al. Hum. Genet. 128(2):195-204(2010) |
1st Image Caption |
Western Blot at 1:2000 dilution + mouse kidney lysate Lysates/proteins at 20 ug per lane. |
2nd Image Caption |
Western Blot at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: HT-29 whole cell lysate Lysates/proteins at 20 ug per lane. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.