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PPT1 Antibody

PPT1 Antibody

Manufacturer	ProSci
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Format	Liquid
Applications	WB
Amount	400 ul
Host	Rabbit
Item no.	PRS-58-985-400ul
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1, PPT1, PPT
Shipping	blue ice or RT
By Research Area	Obesity, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Monkey
Immunogen	This PPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PPT1.
Applications	For WB starting dilution is: 1:1000
Predicted Molecular Weight	34 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	PPT1
Accession #	P50897
Protein Gi #	1709747
Ncbi Gene Id #	5538
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	PPT1
Ncbi Official Full Name	Palmitoyl-protein thioesterase 1
Ncbi Organism	Homo sapiens
Swissprot #	P50897
Background	The protein encoded by this gene is a small glycoproteininvolved in the catabolism of lipid-modified proteins duringlysosomal degradation. The encoded enzyme removes thioester-linkedfatty acyl groups such as palmitate from cysteine residues. Defectsin this gene are a cause of infantile neuronal ceroidlipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis4 (CLN4). Two transcript variants encoding different isoforms havebeen found for this gene.
Background References 1	Ohno, K., et al. Brain Dev. 32(7):524-530(2010)
Background References 2	Simonati, A., et al. Pediatr. Neurol. 40(4):271-276(2009)
Background References 3	Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Background References 4	Kousi, M., et al. Brain 132 (PT 3), 810-819 (2009) :
1st Image Caption	Western blot analysis in A549 cell line lysates (35ug/lane).
2nd Image Caption	Western blot analysis of PPT1 using rabbit polyclonal PPT1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PPT1 gene.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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