Item no. |
PRS-57-975-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, IHC-P |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Transforming growth factor beta-2, TGF-beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, G-TSF, Polyergin, Latency-associated peptide, LAP, TGFB2 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer, Cell Cycle, Obesity, Signal Transduction |
Immunogen |
This TGF Beta 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the C-terminal region of human TGF Beta 2. |
Applications |
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50 |
Predicted Molecular Weight |
48 kDa |
Purification |
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
TGFB2 |
Accession # |
P61812 |
Protein Gi # |
48429157 |
Ncbi Gene Id # |
7042 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
TGFB2 |
Ncbi Official Full Name |
Transforming growth factor beta-2 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P61812 |
Background |
Transforming growth factor-beta 2 (TGF-?2) is a cytokine that performs many cellular functions and has a vital role during embryonic development. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. There are two named isoforms of this protein, created by alternative splicing of the same gene. |
Background References 1 |
Hatsushika, K., Clin. Exp. Allergy 37 (8), 1165-1174 (2007) Jimi, S., Int. J. Oncol. 31 (2), 397-404 (2007) Ito, T., Biochem. Biophys. Res. Commun. 359 (1), 108-114 (2007) Yao, K., Mol. Vis. 13, 1769-1776 (2007) |
1st Image Caption |
Western blot analysis in Raji cell line lysates (35ug/lane). |
2nd Image Caption |
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with TGFB2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.