UBE2D2 Antibody

blue ice or RT

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat, Xenopus

For WB starting dilution is: 1:1000

This antibody is purified through a protein A column, followed by peptide affinity purification.

Rabbit Ig

Supplied in PBS with 0.09% (W/V) sodium azide.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

None

P62837

7322

UBE2D2

Homo sapiens

The modification of proteins with ubiquitin is animportant cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least threeclasses of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-proteinligases, or E3s. This gene encodes a member of the E2ubiquitin-conjugating enzyme family. This enzyme functions in theubiquitination of the tumor-suppressor protein p53, which isinduced by an E3 ubiquitin-protein ligase. Two alternativelyspliced transcript variants have been found for this gene and theyencode distinct isoforms.

Wu, K., et al. Mol. Cell 37(6):784-796(2010)

Sakata, E., et al. Structure 18(1):138-147(2010)