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OTU7B Antibody

OTU7B Antibody

Item no.	PRS-57-615-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	OTU domain-containing protein 7B, Cellular zinc finger anti-NF-kappa-B protein, Zinc finger A20 domain-containing protein 1, Zinc finger protein Cezanne, OTUD7B, ZA20D1
Available
Shipping	blue ice or RT
By Research Area	Cell Cycle, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Mouse
Immunogen	This OTU7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 757-784 amino acids from the C-terminal region of human OTU7B.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight	93 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	OTUD7B
Accession #	Q6GQQ9
Protein Gi #	51701318
Ncbi Gene Id #	56957
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	OTUD7B
Ncbi Official Full Name	OTU domain-containing protein 7B
Ncbi Organism	Homo sapiens
Swissprot #	Q6GQQ9
Background	OTU7B has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.
Background References 1	Bremm, A., et al. Nat. Struct. Mol. Biol. 17(8):939-947(2010)
Background References 2	Jin, Z., et al. Cell 137(4):721-735(2009)
Background References 3	Enesa, K., et al. J. Biol. Chem. 283(27):18582-18590(2008)
Background References 4	Bohgaki, M., et al. Biochim. Biophys. Acta 1783(5):826-837(2008)
1st Image Caption	Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
2nd Image Caption	OTU7B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024

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