Comparison

DRAGON Antibody

Item no. PRS-57-567-400ul
Manufacturer ProSci
Amount 400 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IHC-P
Specific against Human, Mouse
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB
Available
Shipping
blue ice or RT
By Research Area
Neuroscience, Signal Transduction
Immunogen
This DRAGON (RGMB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-406 amino acids from the C-terminal region of human DRAGON (RGMB).
Applications
For WB starting dilution is: 1:2000

For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight
48 kDa
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Clonality
Polyclonal
Isotype
Rabbit Ig
Conjugate
Unconjugated
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration
batch dependent
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications
None
Ncbi Official Symbol
RGMB
Accession #
Q6NW40
Protein Gi #
327478562
Ncbi Gene Id #
285704
User Note
Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol
RGMB
Ncbi Official Full Name
RGM domain family member B
Ncbi Organism
Homo sapiens
Swissprot #
Q6NW40
Background
Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.
Background References 1
Schnichels, S., Gene Expr. Patterns(1), 1-11 (2007)
Background References 2
Metzger, M., Dev. Dyn. 234 (1), 169-175 (2005)
Background References 3
Xia, Y., Endocrinology 146 (8), 3614-3621 (2005)
1st Image Caption
Western Blot at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: mouse brain lysate Lane 3: mouse cerebellum lysate Lane 4: NCI-H460 whole cell lysate Lysates/proteins at 20 ug per lane.
2nd Image Caption
Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with DRAGON (RGMB) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
3rd Image Caption
Western blot analysis of DRAGON (RGMB) Antibody in K562 cell line lysates (35ug/lane)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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