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NONO Antibody

NONO Antibody

Item no.	PRS-57-268-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Non-POU domain-containing octamer-binding protein, NonO protein, 54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, DNA-binding p52/p100 complex, 52 kDa subunit, NMT55, p54(nrb), p54nrb, NONO, NRB54
Available
Shipping	blue ice or RT
Homology	Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen	This NONO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human NONO.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight	54 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	NONO
Accession #	Q15233
Protein Gi #	67469924
Ncbi Gene Id #	4841
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	NONO
Ncbi Official Full Name	Non-POU domain-containing octamer-binding protein
Ncbi Organism	Homo sapiens
Swissprot #	Q15233
Background	This gene encodes an RNA-binding protein which playsvarious roles in the nucleus, including transcriptional regulationand RNA splicing. A rearrangement between this gene and thetranscription factor E3 gene has been observed in papillary renalcell carcinoma. Alternatively spliced transcript variants have beendescribed. Pseudogenes exist on Chromosomes 2 and 16. [provided byRefSeq].
Background References 1	Marko, M., et al. Exp. Cell Res. 316(3):390-400(2010)
Background References 2	Dong, X., et al. Mol. Endocrinol. 23(8):1147-1160(2009)
Background References 3	Sikora, D., et al. Virology 390(1):71-78(2009)
Background References 4	Clemson, C.M., et al. Mol. Cell 33(6):717-726(2009)
1st Image Caption	Western blot analysis in Hela cell line lysates (35ug/lane).
2nd Image Caption	NONO Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024