LGALS3 Antibody

Cell Cycle, Neuroscience

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

This antibody is purified through a protein A column, followed by peptide affinity purification.

Rabbit Ig

Supplied in PBS with 0.09% (W/V) sodium azide.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

None

P17931

3958

LGALS3

Homo sapiens

This gene encodes a member of the galectin family ofcarbohydrate binding proteins. Members of this protein family havean affinity for beta-galactosides. The encoded protein ischaracterized by an N-terminal proline-rich tandem repeat domainand a single C-terminal carbohydrate recognition domain. Thisprotein can self-associate through the N-terminal domain allowingit to bind to multivalent saccharide ligands. This proteinlocalizes to the extracellular matrix, the cytoplasm and thenucleus. This protein plays a role in numerous cellular functionsincluding apoptosis, innate immunity, cell adhesion and T-cellregulation. Alternate splicing results in multiple transcriptvariants.

Debierre-Grockiego, F., et al. J. Biol. Chem. 285(43):32744-32750(2010)

Markowska, A.I., et al. J. Exp. Med. 207(9):1981-1993(2010)

Western Blot at 1:1000 dilution + U118MG whole cell lysate Lysates/proteins at 20 ug per lane.

LGALS3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.