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MOSC2 Antibody

MOSC2 Antibody

Item no.	PRS-57-129-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitochondrial amidoxime reducing component 2, mARC2, 1---, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2, MOSC domain-containing protein 2, Moco sulfurase C-terminal domain-containing protein 2, MARC2, MOSC2
Available
Shipping	blue ice or RT
By Research Area	Obesity, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen	This MOSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the C-terminal region of human MOSC2.
Applications	For WB starting dilution is: 1:1000
Predicted Molecular Weight	38 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	MARCH2
Accession #	Q969Z3
Protein Gi #	74760692
Ncbi Gene Id #	54996
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	MARCH2
Ncbi Official Full Name	Mitochondrial amidoxime reducing component 2
Ncbi Organism	Homo sapiens
Swissprot #	Q969Z3
Background	Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.
Background References 1	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background References 2	Aberg, K., et al. Biol. Psychiatry 67(3):279-282(2010)
Background References 3	Havemeyer, A., et al. J. Biol. Chem. 281(46):34796-34802(2006)
Background References 4	Anantharaman, V., et al. FEMS Microbiol. Lett. 207(1):55-61(2002)
1st Image Caption	Western blot analysis in mouse spleen tissue lysates (35ug/lane).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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