Item no. |
PRS-56-873-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Hemogen, Erythroid differentiation-associated gene protein, EDAG-1, Hemopoietic gene protein, Negative differentiation regulator protein, HEMGN, EDAG, NDR |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Signal Transduction |
Immunogen |
This HEMGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human HEMGN. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
55 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
HEMGN |
Accession # |
Q9BXL5 |
Protein Gi # |
74752432 |
Ncbi Gene Id # |
55363 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
HEMGN |
Ncbi Official Full Name |
Hemogen |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q9BXL5 |
Background |
HEMGN regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB). |
Background References 1 |
Ding, Y.L., et al. J. Cell. Biochem. 110(4):866-874(2010) |
Background References 2 |
Moreno, L.M., et al. Hum. Mol. Genet. 18(24):4879-4896(2009) |
Background References 3 |
Lowe, J.K., et al. PLoS Genet.(2), E1000365 (2009) : |
Background References 4 |
Li, C.Y., et al. Biochim. Biophys. Acta 1779(10):606-615(2008) |
1st Image Caption |
Western blot analysis in A549 cell line lysates (35ug/lane). |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.