Item no. |
PRS-56-835-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Granulysin, Lymphokine LAG-2, Protein NKG5, T-cell activation protein 519, GNLY, LAG2, NKG5, TLA519 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Immunology |
Immunogen |
This GNLY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human GNLY. |
Applications |
For WB starting dilution is: 1:1000 |
Predicted Molecular Weight |
16 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
GNLY |
Accession # |
P22749 |
Protein Gi # |
116242500 |
Ncbi Gene Id # |
10578 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
GNLY |
Ncbi Official Full Name |
Granulysin |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P22749 |
Background |
The product of this gene is a member of the saposin-likeprotein (SAPLIP) family and is located in the cytotoxic granules ofT cells, which are released upon antigen stimulation. This proteinis present in cytotoxic granules of cytotoxic T lymphocytes andnatural killer cells, and it has antimicrobial activity against M.tuberculosis and other organisms. Alternatively spliced transcriptvariants encoding different isoforms have been identified. |
Background References 1 |
Xing, J., et al. J. Immunol. 185(9):5074-5081(2010) |
Background References 2 |
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010) |
Background References 3 |
Davila, S., et al. Genes Immun. 11(3):232-238(2010) |
Background References 4 |
Yang, C., et al. Int. J. Tuberc. Lung Dis. 13(11):1360-1366(2009) |
1st Image Caption |
Western blot analysis in MDA-MB435 cell line lysates (35ug/lane). |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.