SCP2 Antibody

Cancer, Obesity, Signal Transduction

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

This antibody is purified through a protein A column, followed by peptide affinity purification.

Rabbit Ig

Supplied in PBS with 0.09% (W/V) sodium azide.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

None

P22307

6342

SCP2

Homo sapiens

This gene encodes two proteins: sterol carrier protein X(SCPx) and sterol carrier protein 2 (SCP2), as a result oftranscription initiation from 2 independently regulated promoters.The transcript initiated from the proximal promoter encodes thelonger SCPx protein, and the transcript initiated from the distalpromoter encodes the shorter SCP2 protein, with the 2 proteinssharing a common C-terminus. Evidence suggests that the SCPxprotein is a peroxisome-associated thiolase that is involved in theoxidation of branched chain fatty acids, while the SCP2 protein isthought to be an intracellular lipid transfer protein. This gene ishighly expressed in organs involved in lipid metabolism, and mayplay a role in Zellweger syndrome, in which cells are deficient inperoxisomes and have impaired bile acid synthesis. Alternativesplicing of this gene produces multiple transcript variants, someencoding different isoforms.

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)

Rikova, K., et al. Cell 131(6):1190-1203(2007)

SCP2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.