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SRGN Antibody

SRGN Antibody

Item no.	PRS-56-327-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Western Blot Cell Stainings ECM Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serglycin, Hematopoietic proteoglycan core protein, Platelet proteoglycan core protein, PPG, Secretory granule proteoglycan core protein, SRGN, PRG, PRG1
Available
Shipping	blue ice or RT
By Research Area	Cell Cycle, Obesity, Signal Transduction
Immunogen	This SRGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the C-terminal region of human SRGN.
Applications	For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Predicted Molecular Weight	18 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	SRGN
Accession #	P10124
Protein Gi #	269849659
Ncbi Gene Id #	5552
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	SRGN
Ncbi Official Full Name	Serglycin
Ncbi Organism	Homo sapiens
Swissprot #	P10124
Background	This gene encodes a protein best known as a hematopoieticcell granule proteoglycan. Proteoglycans stored in the secretorygranules of many hematopoietic cells also contain aprotease-resistant peptide core, which may be important forneutralizing hydrolytic enzymes. This encoded protein was found tobe associated with the macromolecular complex of granzymes andperforin, which may serve as a mediator of granule-mediatedapoptosis. Two transcript variants, only one of themprotein-coding, have been found for this gene. [provided byRefSeq].
Background References 1	Ma, D., et al. Pediatr Blood Cancer 50(5):1067-1069(2008)
Background References 2	Kolset, S.O., et al. Glycoconj. J. 25(4):305-311(2008)
Background References 3	Theocharis, A.D., et al. J. Biol. Chem. 281(46):35116-35128(2006)
Background References 4	Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
1st Image Caption	Western blot analysis in Hela cell line lysates (35ug/lane).
2nd Image Caption	Flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024