Item no. |
PRS-56-327-400ul |
Manufacturer |
ProSci
|
Amount |
400 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, FC |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Serglycin, Hematopoietic proteoglycan core protein, Platelet proteoglycan core protein, PPG, Secretory granule proteoglycan core protein, SRGN, PRG, PRG1 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Cell Cycle, Obesity, Signal Transduction |
Immunogen |
This SRGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from the C-terminal region of human SRGN. |
Applications |
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50 |
Predicted Molecular Weight |
18 kDa |
Purification |
This antibody is purified through a protein A column, followed by peptide affinity purification. |
Clonality |
Polyclonal |
Isotype |
Rabbit Ig |
Conjugate |
Unconjugated |
Buffer |
Supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration |
batch dependent |
Storage Conditions |
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
SRGN |
Accession # |
P10124 |
Protein Gi # |
269849659 |
Ncbi Gene Id # |
5552 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
SRGN |
Ncbi Official Full Name |
Serglycin |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P10124 |
Background |
This gene encodes a protein best known as a hematopoieticcell granule proteoglycan. Proteoglycans stored in the secretorygranules of many hematopoietic cells also contain aprotease-resistant peptide core, which may be important forneutralizing hydrolytic enzymes. This encoded protein was found tobe associated with the macromolecular complex of granzymes andperforin, which may serve as a mediator of granule-mediatedapoptosis. Two transcript variants, only one of themprotein-coding, have been found for this gene. [provided byRefSeq]. |
Background References 1 |
Ma, D., et al. Pediatr Blood Cancer 50(5):1067-1069(2008) |
Background References 2 |
Kolset, S.O., et al. Glycoconj. J. 25(4):305-311(2008) |
Background References 3 |
Theocharis, A.D., et al. J. Biol. Chem. 281(46):35116-35128(2006) |
Background References 4 |
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006) |
1st Image Caption |
Western blot analysis in Hela cell line lysates (35ug/lane). |
2nd Image Caption |
Flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.