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DVL3 Antibody

DVL3 Antibody

Item no.	PRS-56-188-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Immunohistochemistry Western Blot Immunofluorescence Cardiovascular Research Thrombosis & Hemostasis Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC-P
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Segment polarity protein dishevelled homolog DVL-3, Dishevelled-3, DSH homolog 3, DVL3, KIAA0208
Available
Shipping	blue ice or RT
By Research Area	Neuroscience, Signal Transduction
Immunogen	This DVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-557 amino acids from the C-terminal region of human DVL3.
Applications	For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50
Predicted Molecular Weight	78 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	DVL3
Accession #	Q92997
Protein Gi #	6919875
Ncbi Gene Id #	1857
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	DVL3
Ncbi Official Full Name	Segment polarity protein dishevelled homolog DVL-3
Ncbi Organism	Homo sapiens
Swissprot #	Q92997
Background	This gene is a member of a multi-gene family which sharesstrong similarity with the Drosophila dishevelled gene, dsh. TheDrosophila dishevelled gene encodes a cytoplasmic phosphoproteinthat regulates cell proliferation.
Background References 1	Gnad, T., et al. Mol. Cancer 9, 31 (2010) :
Background References 2	Bouteille, N., et al. Oncogene 28(28):2569-2580(2009)
Background References 3	Fukukawa, C., et al. Oncogene 28(8):1110-1120(2009)
Background References 4	Wei, Q., et al. Lung Cancer 62(2):181-192(2008)
1st Image Caption	Western Blot at 1:2000 dilution Lane 1: A549 whole cell lysates Lane 2: NIH/3T3 whole cell lysates Lane 3: K562 whole cell lysates Lysates/proteins at 20 ug per lane.
2nd Image Caption	DVL3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.
3rd Image Caption	Confocal immunofluorescent analysis of DVL3 Antibody with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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