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EIF2B4 Antibody

EIF2B4 Antibody

Item no.	PRS-55-715-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Translation initiation factor eIF-2B subunit delta, eIF-2B GDP-GTP exchange factor subunit delta, EIF2B4, EIF2BD
Available
Shipping	blue ice or RT
Homology	Predicted species reactivity based on immunogen sequence: Bovine
Immunogen	This EIF2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-175 amino acids from the Central region of human EIF2B4.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight	58 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	EIF2B4
Accession #	Q9UI10
Protein Gi #	28381357
Ncbi Gene Id #	8890
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	EIF2B4
Ncbi Official Full Name	Translation initiation factor eIF-2B subunit delta
Ncbi Organism	Homo sapiens
Swissprot #	Q9UI10
Background	Eukaryotic initiation factor 2B (EIF2B), which isnecessary for protein synthesis, is a GTP exchange factor composedof five different subunits. The protein encoded by this gene is thefourth, or delta, subunit. Defects in this gene are a cause ofleukoencephalopathy with vanishing white matter (VWM) andovarioleukodystrophy. Multiple transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
Background References 1	Naukkarinen, J., et al. PLoS Genet.(6), E1000976 (2010) :
Background References 2	Wu, Y., et al. J. Hum. Genet. 54(2):74-77(2009)
Background References 3	Horzinski, L., et al. PLoS ONE(12), E8318 (2009) :
Background References 4	Pronk, J., et al. Mult. Scler. 14(8):1123-1126(2008)
1st Image Caption	Western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EIF2B4 antibody detected the EIF2B4 protein (arrow).
2nd Image Caption	Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the EIF2B4 antibody detected the EIF2B4 protein (arrow).
3rd Image Caption	E immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of E for immunohistochemistry.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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