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PPM1L Antibody

PPM1L Antibody

Item no.	PRS-55-550-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC-P
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Protein phosphatase 1L, Protein phosphatase 1-like, Protein phosphatase 2C isoform epsilon, PP2C-epsilon, PPM1L, PP2CE
Available
Shipping	blue ice or RT
By Research Area	Cancer, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Bovine
Immunogen	This PPM1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human PPM1L.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100
Predicted Molecular Weight	41 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	PPM1L
Accession #	Q5SGD2
Protein Gi #	74743437
Ncbi Gene Id #	151742
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	PPM1L
Ncbi Official Full Name	Protein phosphatase 1L
Ncbi Organism	Homo sapiens
Swissprot #	Q5SGD2
Background	PPM1L, or PP2CE, belongs to the PP2C group ofserine/threonine phosphatases, which are distinguished from otherphosphatases by their structure, absolute requirement for Mg(2+) orMn(2+), and insensitivity to okadaic acid. PP2Cs regulatestress-activated protein kinase (SAPK; see MIM 601158) signalingcascades that respond to extracellular stimuli (Jin et al., 2004[PubMed 15560375]).
Background References 1	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background References 2	Thean, L.F., et al. Genes Chromosomes Cancer 49(2):99-106(2010)
Background References 3	Trynka, G., et al. Gut 58(8):1078-1083(2009)
Background References 4	Saito, S., et al. J. Biol. Chem. 283(10):6584-6593(2008)
1st Image Caption	Western blot analysis in mouse heart tissue lysates (35ug/lane).
2nd Image Caption	PPM1L antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/6/2024

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