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GGTLC2 Antibody

GGTLC2 Antibody

Item no.	PRS-55-092-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC, IHC-P
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Gamma-glutamyltransferase light chain 2, Gamma-glutamyltransferase-like protein 4, GGTLC2, GGTL4
Available
Shipping	blue ice or RT
By Research Area	Obesity, Signal Transduction
Homology	Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Immunogen	This GGTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-154 amino acids from the Central region of human GGTLC2.
Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50
Predicted Molecular Weight	24 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	GGTLC2
Accession #	Q14390
Protein Gi #	294862536
Ncbi Gene Id #	91227
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	GGTLC2
Ncbi Official Full Name	Gamma-glutamyltransferase light chain 2
Ncbi Organism	Homo sapiens
Swissprot #	Q14390
Background	Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is amembrane-bound extracellular enzyme that cleaves gamma-glutamylpeptide bonds in glutathione and other peptides and transfers thegamma-glutamyl moiety to acceptors. Autocatalytic cleavage of theGGT1 precursor polypeptide produces a heavy chain and a light chainthat associate with each other to form the functional enzyme. Lightchain-only GGTs, such as GGTLC2, contain a region corresponding tothe GGT1 light chain, but they lack the membrane-anchoring heavychain region (Heisterkamp et al., 2008 [PubMed 18357469]).[suppliedby OMIM].
Background References 1	Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008)
Background References 2	Dunham, I., et al. Nature 402(6761):489-495(1999)
Background References 3	Kawasaki, K., et al. Genome Res. 7(3):250-261(1997)
Background References 4	Leh, H., et al. FEBS Lett. 394(3):258-262(1996)
1st Image Caption	Western blot analysis in U251 cell line lysates (35ug/lane).
2nd Image Caption	GGTLC2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
3rd Image Caption	Flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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