Item no. |
PRS-45-448-0.1mg |
Manufacturer |
ProSci
|
Amount |
0.1 mg |
Category |
|
Type |
Antibody Primary |
Format |
Liquid |
Applications |
FC, ELISA |
Specific against |
Human |
Host |
Goat |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
CYP3A4, cytochrome P450, family 3, subfamily A, polypeptide 4 , HGNC:2637, CP33, CP34, CYP3A, CYP3A3, HLP, NF-25, P450C3, P450PCN1, P450-III, steroid inducible, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfami |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Cancer , Infectious Disease |
Immunogen |
The immunogen for this antibody is: C-KESRLEDTQKHR |
Applications |
Peptide ELISA: antibody detection limit dilution 1:8000.Flow Cytometry: Flow cytometric analysis of HepG2 cells. Recommended concentration: 10ug/ml. |
Specificity |
This antibody is expected to recognise both reported isoforms (NP_059488.2; NP_001189784.1) and it is not expected to cross-react with 3A5, 3A7 ot 3A43. |
Purification |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.Aliquot and store at -20°C. Minimize freezing and thawing. |
Concentration |
500 ug/mL |
Storage Conditions |
Aliquot and store at -20˚ C. Minimize freezing and thawing. |
Related Products |
Cat. No. 45-448P - CYP3A4 Peptide |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
CYP3A4 |
Accession # |
NP_059488.2, NP_001189784.1 |
Protein Gi # |
13435386 |
Ncbi Gene Id # |
1576 |
Ncbi Official Symbol |
CYP3A4 |
Ncbi Official Full Name |
cytochrome P450, family 3, subfamily A, polypeptide 4 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P08684 |
Background References 1 |
Choi MH, Skipper PL, Wishnok JS, Tannenbaum SR. Characterization of testosterone 11{beta}-hydroxylation catalyzed by human-liver microsomal cytochromes P450. Drug Metab Dispos. 2005 Mar 11; |
1st Image Caption |
45-448 Flow cytometric analysis of paraformaldehyde fixed HepG2 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) fo |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.