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ST2 Antibody [ST33868]

ST2 Antibody [ST33868]

Item no.	PRS-36-046-100ug
Manufacturer	ProSci
Amount	100 ug
Category	Food Safety Allergenes Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Antibodies Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, ELISA
Specific against	Human
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Interleukin-1 Receptor-like 1; IL-1 Receptor-like 1; IL1RL1; IL-33 Receptor; Interleukin-33 Receptor
Available
Shipping	blue ice or RT
By Research Area	Innate Immunity
Immunogen	Recombinant human soluble ST2.
Applications	ELISA: (direct or indirect: 1:2, 000-1:5, 000). Western blot: (1:2, 000-1:5, 000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.
Specificity	Recognizes human ST2.
Clonality	Monoclonal
Clone	ST33868
Isotype	IgG1, kappa
Conjugate	Unconjugated
Buffer	Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration	1 mg/ml
Storage Conditions	Stable for at least 1 year after receipt when stored at -20˚ C.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	IL1RL1
Accession #	116242527
Protein Gi #	Q01638
Ncbi Gene Id #	9173
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	IL1RL1
Ncbi Official Full Name	interleukin 1 receptor like 1
Ncbi Organism	Homo sapiens
Swissprot #	Q01638
Background	The ST2 gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/6/2024