Item no. |
PRS-30-076-100ul |
Manufacturer |
ProSci
|
Amount |
100 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, ELISA |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
RARB, HAP, NR1B2, RRB2, MCOPS12 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Transcription , Cancer , Signal Transduction |
Immunogen |
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RARB. |
Applications |
RARB antibody can be used for detection of RARB by ELISA at 1:62500. RARB antibody can be used for detection of RARB by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. |
Positive Control 1 |
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate |
Predicted Molecular Weight |
50 kDa |
Purification |
Antibody is purified by peptide affinity chromatography method. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration |
batch dependent |
Storage Conditions |
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RARB antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles. |
Disclaimer |
This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
RARB |
Accession # |
NP_000956 |
Protein Gi # |
14916494 |
Ncbi Gene Id # |
5915 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
RARB |
Ncbi Official Full Name |
retinoic acid receptor, beta |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P10826 |
Background |
RARB is a retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. |
Background References 1 |
Uhl, G.R., (2008) Arch. Gen. Psychiatry 65 (6), 683-693. |
1st Image Caption |
Antibody used in WB on Human brain at 0.2-1 ug/ml. |
2nd Image Caption |
Antibody used in IHC on Human brain. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.