Item no. |
PRS-29-825-100ul |
Manufacturer |
ProSci
|
Amount |
100 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, IHC, ELISA |
Specific against |
Human, Mouse, Rat, Canine |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
FKBP6, FKBP36, MGC87179, PPIase |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Apoptosis , Homeostasis |
Immunogen |
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FKBP6. |
Applications |
FKBP6 antibody can be used for detection of FKBP6 by ELISA at 1:1562500. FKBP6 antibody can be used for detection of FKBP6 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. |
Positive Control 1 |
Cat. No. 1211 - HepG2 Cell Lysate |
Predicted Molecular Weight |
53 kDa, 53 kDa |
Purification |
Antibody is purified by protein A chromatography method. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration |
batch dependent |
Storage Conditions |
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store FKBP6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles. |
Disclaimer |
This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
FKBP6 |
Accession # |
NP_003593 |
Protein Gi # |
146229346 |
Ncbi Gene Id # |
8468 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
FKBP6 |
Ncbi Official Full Name |
FK506 binding protein 6, 36kDa |
Ncbi Organism |
Homo sapiens |
Swissprot # |
O75344 |
Background |
FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation. |
Background References 1 |
Ye, X.Q., (2005) Int. J. Mol. Med. 16 (5), 851-856. |
1st Image Caption |
Antibody used in IHC on Human kidney. |
2nd Image Caption |
Antibody used in WB on Human HepG2 at 1.25 ug/ml. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.