KEAP1 Antibody

Transcription , Cancer

KEAP1 antibody can be used for detection of KEAP1 by ELISA at 1:1562500. KEAP1 antibody can be used for detection of KEAP1 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

70 kDa, 70 kDa

Polyclonal

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KEAP1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

None

NP_987096

9817

KEAP1

Homo sapiens

KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Antibody used in IHC on Human kidney.

Antibody used in WB on HepG2 at 1.25 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).