Item no. |
PRS-26-792-100ul |
Manufacturer |
ProSci
|
Amount |
100 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, ELISA |
Specific against |
Human |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
GEFT, p63RhoGEF, GEFT |
Available |
|
Shipping |
blue ice or RT |
Immunogen |
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GEFT. |
Applications |
GEFT antibody can be used for detection of GEFT by ELISA at 1:312500. GEFT antibody can be used for detection of GEFT by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. |
Positive Control 1 |
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate |
Predicted Molecular Weight |
64 kDa |
Purification |
Antibody is purified by peptide affinity chromatography method. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration |
batch dependent |
Storage Conditions |
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GEFT antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles. |
Disclaimer |
This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
ARHGEF25 |
Accession # |
NP_891992 |
Protein Gi # |
150417975 |
Ncbi Gene Id # |
115557 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
ARHGEF25 |
Ncbi Official Full Name |
Rho guanine nucleotide exchange factor (GEF) 25 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q86VW2 |
Background |
The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]). |
Background References 1 |
Lutz, S., (2007) Science 318 (5858), 1923-1927. |
1st Image Caption |
Antibody used in WB on Human Brain at 0.2-1 ug/ml. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.