Item no. |
PRS-26-024-100ul |
Manufacturer |
ProSci
|
Amount |
100 ul |
Category |
|
Type |
Antibody Polyclonal |
Format |
Liquid |
Applications |
WB, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
LFNG, SCDO3 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Membrane |
Immunogen |
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LFNG. |
Applications |
LFNG antibody can be used for detection of LFNG by ELISA at 1:62500. LFNG antibody can be used for detection of LFNG by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000. |
Positive Control 1 |
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate |
Predicted Molecular Weight |
39 kDa |
Purification |
Antibody is purified by peptide affinity chromatography method. |
Clonality |
Polyclonal |
Conjugate |
Unconjugated |
Buffer |
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration |
batch dependent |
Storage Conditions |
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store LFNG antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles. |
Disclaimer |
This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
LFNG |
Accession # |
NP_001035258 |
Protein Gi # |
93141005 |
Ncbi Gene Id # |
3955 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
LFNG |
Ncbi Official Full Name |
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q8NES3-3 |
Background |
LFNG is a member of the glycosyltransferase superfamily. It is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in the gene that encodes this protein have been associated with autosomal recessive spondylocostal dysostosis 3. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized. |
Background References 1 |
Sparrow, D.B., (2006) Am. J. Hum. Genet. 78 (1), 28-37. |
1st Image Caption |
Antibody used in WB on Human Muscle at 0.2-1 ug/ml. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.