« Back
Home /
FANCL Antibody

FANCL Antibody

Item no.	PRS-22-497-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FANCL, POG, PHF9, PHD finger protein 9, FLJ10335, Fanconi anemia, complementation group L, FAAP43
Available
Shipping	blue ice or RT
By Research Area	Cell Cycle
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human FANCL (NP_060532.2).
Applications	WB: 1:200 - 1:2000 IHC: 1:20 - 1:200
Positive Control 1	Mouse thymus
Predicted Molecular Weight	Observed: 38kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	FANCL
Ncbi Gene Id #	55120
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	FANCL
Ncbi Official Full Name	Fanconi anemia, complementation group L
Ncbi Organism	Homo sapiens
Swissprot #	Q9NW38
Background	The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.
1st Image Caption	Western blot analysis of extracts of mouse thymus, using FANCL antibody (22-497) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
2nd Image Caption	Immunohistochemistry of paraffin-embedded mouse stomach using FANCL antibody (22-497) at dilution of 1:100 (40x lens).
3rd Image Caption	Immunohistochemistry of paraffin-embedded human esophagus using FANCL antibody (22-497) at dilution of 1:100 (40x lens).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 50 uL

available

Delivery expected until 10/4/2024

Express Delivery: Save 14 days

Compare

Add to wishlist

Recommend by mail