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CCBL1 Antibody

CCBL1 Antibody

Item no.	PRS-22-298-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CCBL1, cysteine conjugate-beta lyase, glutamine transaminase K, kyneurenine aminotransferase, GTK, KATI, MGC29624, cytoplasmic cysteine conjugate-beta lyase, glutamine-phenylpyruvate aminotransferase, kynurenine aminotransferase I, KAT1
Available
Shipping	blue ice or RT
By Research Area	Cancer, Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCBL1 (NP_001116144.1).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:10 - 1:100
Positive Control 1	Raji
Positive Control 2	HeLa
Positive Control 3	SW620
Positive Control 4	Mouse liver
Positive Control 5	Mouse kidney
Positive Control 6	Mouse heart
Predicted Molecular Weight	Observed: 48kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	CCBL1
Ncbi Gene Id #	883
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	CCBL1
Ncbi Official Full Name	cysteine conjugate-beta lyase, cytoplasmic
Ncbi Organism	Homo sapiens
Swissprot #	Q16773
Background	This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
1st Image Caption	Western blot analysis of extracts of various cell lines, using CCBL1 Antibody (22-298) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
2nd Image Caption	Immunohistochemistry of paraffin-embedded mouse liver using CCBL1 antibody (22-298) at dilution of 1:100 (40x lens).
3rd Image Caption	Immunohistochemistry of paraffin-embedded mouse heart using CCBL1 antibody (22-298) at dilution of 1:100 (40x lens).
4th Image Caption	Immunofluorescence analysis of U2OS cells using CCBL1 antibody (22-298). Blue: DAPI for nuclear staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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Delivery expected until 9/6/2024

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