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PTK6 Antibody

PTK6 Antibody

Item no.	PRS-19-112-100uL
Manufacturer	ProSci
Amount	100 uL
Category	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Primary Antibodies By Organ Breast Cancer
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BRK, Breast tumor kinaseBRK
Available
Shipping	blue ice or RT
By Research Area	Cancer, Signal Transduction
Immunogen	A synthetic peptide of human PTK6
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Positive Control 1	MCF7
Predicted Molecular Weight	Observed: 52kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, pH7.3.
Storage Conditions	Store at 4˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	PTK6
Ncbi Gene Id #	5753
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	PTK6
Ncbi Official Full Name	protein tyrosine kinase 6
Ncbi Organism	Homo sapiens
Swissprot #	Q13882
Background	The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.
1st Image Caption	Western blot analysis of extracts of MCF-7 cells, using PTK6 antibody (19-112). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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