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SLC1A1 Antibody

SLC1A1 Antibody

Item no.	PRS-18-862-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Oncology Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DCBXA, EAAC1, EAAT3, SCZD18, excitatory amino acid transporter 3, excitatory amino acid carrier 1, neuronal and epithelial glutamate transporter, sodium-dependent glutamate/aspartate transporter 3, solute carrier family 1 (neuronal/epithelial high affinit
Available
Shipping	blue ice or RT
By Research Area	Neuroscience
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 430-524 of human SLC1A1 (NP_004161.4).
Applications	WB: 1:500 - 1:2000 IF: 1:50 - 1:200
Positive Control 1	SKOV3
Positive Control 2	HT-29
Predicted Molecular Weight	Observed: 71kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	SLC1A1
Ncbi Gene Id #	6505
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	SLC1A1
Ncbi Official Full Name	solute carrier family 1 member 1
Ncbi Organism	Homo sapiens
Swissprot #	P43005
Background	This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.
1st Image Caption	Western blot analysis of extracts of various cell lines, using SLC1A1 antibody (18-862) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
2nd Image Caption	Immunofluorescence analysis of rat brain using SLC1A1 antibody (18-862) at dilution of 1:100. Blue: DAPI for nuclear staining.
3rd Image Caption	Immunofluorescence analysis of mouse brain using SLC1A1 antibody (18-862) at dilution of 1:100. Blue: DAPI for nuclear staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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Delivery expected until 9/6/2024

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