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ACTL6A Antibody

ACTL6A Antibody

Item no.	PRS-18-581-100uL
Manufacturer	ProSci
Amount	100 uL
Category	Oncology Antibodies By Cell Type Carcinoma Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IF
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ACTL6, ARPN-BETA, Arp4, BAF53A, INO80K, actin-like protein 6A, 53 kDa BRG1-associated factor A, BAF complex 53 kDa subunit, BAF53, BRG1-associated factor 53A, INO80 complex subunit K, actin-related protein 4, actin-related protein Baf53a, arpNbeta, hArpN
Available
Shipping	blue ice or RT
By Research Area	Cell Cycle, Signal Transduction
Immunogen	A synthetic peptide of human ACTL6A
Applications	WB: 1:500 - 1:2000 IF: 1:20 - 1:50
Positive Control 1	HeLa
Positive Control 2	K-562
Predicted Molecular Weight	Observed: 50kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, pH7.3.
Storage Conditions	Store at 4˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	ACTL6A
Ncbi Gene Id #	86
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	ACTL6A
Ncbi Official Full Name	actin like 6A
Ncbi Organism	Homo sapiens
Swissprot #	O96019
Background	This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
1st Image Caption	Western blot analysis of extracts of various cell lines, using ACTL6A antibody (18-581). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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