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TNFAIP3 Antibody

TNFAIP3 Antibody

Item no.	PRS-18-521-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Neural Development Antibodies By Cell Type Blastoma Hematology Lymphoma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A2AISBL, OTUD7C, TNFA1P2, tumor necrosis factor alpha-induced protein 3, OTU domain-containing protein 7C, putative DNA-binding protein A2tumor necrosis factor inducible protein A2tumor necrosis factor, alpha induced protein 3, zinc finger protein A20
Available
Shipping	blue ice or RT
By Research Area	Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Innate Immunity, Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human TNFAIP3 (NP_006281.1).
Applications	WB: 1:500 - 1:2000
Positive Control 1	Jurkat
Positive Control 2	HepG2
Positive Control 3	SW480
Positive Control 4	Mouse spleen
Predicted Molecular Weight	Observed: 80kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	TNFAIP3
Ncbi Gene Id #	7128
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	TNFAIP3
Ncbi Official Full Name	TNF alpha induced protein 3
Ncbi Organism	Homo sapiens
Swissprot #	P21580
Background	This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
1st Image Caption	Western blot analysis of extracts of various cell lines, using TNFAIP3 antibody (18-521) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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Delivery expected until 10/4/2024

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