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NTRK1 Antibody

NTRK1 Antibody

Item no.	PRS-18-498-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Necrosis Cytoskeleton Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies Microfilaments By Organ Colorectal Cancer Thyroid Cancer
Type	Antibody Primary
Format	Liquid
Applications	WB, IF, IHC
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NTRK1, Oncogene TRK, TrkA/NGF receptor, Tropomyosin-related kinase A, TRK, TRK1, Tyrosine kinase receptor, Tyrosine kinase receptor A, gp140trk, MTC, p140-TrkA, Trk-A, TRKA
Available
Shipping	blue ice or RT
By Research Area	Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NTRK1 (NP_002520.2).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200
Positive Control 1	HeLa
Positive Control 2	K-562
Positive Control 3	NIH/3T3
Positive Control 4	Mouse liver
Positive Control 5	Mouse heart
Positive Control 6	Rat liver
Predicted Molecular Weight	Observed: 110kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	NTRK1
Ncbi Gene Id #	4914
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	NTRK1
Ncbi Official Full Name	neurotrophic tyrosine kinase, receptor, type 1
Ncbi Organism	Homo sapiens
Swissprot #	P04629
Background	This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
1st Image Caption	Western blot analysis of extracts of various cell lines, using NTRK1 antibody (18-498) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
2nd Image Caption	Immunohistochemistry of paraffin-embedded mouse stomach using NTRK1 Antibody (18-498) at dilution of 1:100 (40x lens).
3rd Image Caption	Immunohistochemistry of paraffin-embedded rat cerebellum using NTRK1 Antibody (18-498) at dilution of 1:100 (40x lens).
4th Image Caption	Immunofluorescence analysis of U2OS cells using TRKA antibody (18-498) at dilution of 1:100. Blue: DAPI for nuclear staining.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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Delivery expected until 9/6/2024

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