Item no. |
PRS-15-704-50uL |
Manufacturer |
ProSci
|
Amount |
50 uL |
Category |
|
Type |
Antibody Primary |
Format |
Liquid |
Applications |
WB, IF, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
SMAD6, AOVD2, MADH6, MADH7, HsT17432 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Cell Cycle, Signal Transduction, Stem Cell, Transcription |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human SMAD6 (NP_005576.3). |
Applications |
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200 |
Purification |
Affinity purification |
Clonality |
Polyclonal |
Isotype |
IgG |
Conjugate |
Unconjugated |
Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage Conditions |
Store at -20˚ C. Avoid freeze / thaw cycles. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
SMAD6 |
Ncbi Gene Id # |
4091 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
SMAD6 |
Ncbi Official Full Name |
SMAD family member 6 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
O43541 |
Background |
The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene. |
1st Image Caption |
Immunohistochemistry of paraffin-embedded rat brain using SMAD6 antibody (15-704) at dilution of 1:100 (40x lens). |
2nd Image Caption |
Immunofluorescence analysis of NIH-3T3 cells using SMAD6 antibody (15-704) at dilution of 1:100. Blue: DAPI for nuclear staining. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.