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BGLAP Antibody

BGLAP Antibody

Item no.	PRS-15-643-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BGLAP, bone gamma-carboxyglutamate (gla) protein, BGP, OC, OTTHUMP00000016586, bone Gla protein, bone gamma-carboxyglutamate (gla) protein (osteocalcin), gamma-carboxyglutamic acid-containing protein, osteocalcin
Available
Shipping	blue ice or RT
By Research Area	Cell Cycle, Signal Transduction, Stem Cell
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BGLAP (NP_954642.1).
Applications	WB: 1:500 - 1:2000
Positive Control 1	U-251MG
Positive Control 2	Mouse pancreas
Predicted Molecular Weight	Observed: 11kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	BGLAP
Ncbi Gene Id #	632
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	BGLAP
Ncbi Official Full Name	bone gamma-carboxyglutamate (gla) protein
Ncbi Organism	Homo sapiens
Swissprot #	P02818
Background	This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
1st Image Caption	Western blot analysis of extracts of mouse pancreas, using BGLAP antibody (15-643) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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Delivery expected until 9/6/2024