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DSP Antibody

DSP Antibody

Item no.	PRS-14-900-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC
Specific against	Human, Mouse
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DSP, DPI, desmoplakin I, desmoplakin, 250kDa paraneoplastic pemphigus antigen, DP, DPII
Available
Shipping	blue ice or RT
By Research Area	Cell Cycle, Signal Transduction
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 2750-2850 of human DSP (NP_004406.2).
Applications	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Positive Control 1	HepG2
Predicted Molecular Weight	Observed: 315kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	DSP
Ncbi Gene Id #	1832
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	DSP
Ncbi Official Full Name	desmoplakin
Ncbi Organism	Homo sapiens
Swissprot #	P15924
Background	This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.
1st Image Caption	Western blot analysis of extracts of HepG2 cells, using DSP antibody (14-900) at 1:800 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.
2nd Image Caption	Immunohistochemistry of paraffin-embedded human gastric cancer using DSP antibody (14-900) at dilution of 1:100 (40x lens).
3rd Image Caption	Immunohistochemistry of paraffin-embedded mouse heart using DSP antibody (14-900) at dilution of 1:100 (40x lens).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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Delivery expected until 9/6/2024

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