Item no. |
PRS-14-246-50uL |
Manufacturer |
ProSci
|
Amount |
50 uL |
Category |
|
Type |
Antibody Primary |
Format |
Liquid |
Applications |
WB, IHC |
Specific against |
Human, Rat |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
PERQ amino acid-rich with GYF domain-containing protein 2, GRB10-interacting GYF protein 2, Trinucleotide repeat-containing gene 15 protein, GIGYF2, KIAA0642, PERQ2, TNRC15 |
Available |
|
Shipping |
blue ice or RT |
By Research Area |
Neuroscience |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 350-500 of human GIGYF2 (NP_001096617.1). |
Applications |
WB: 1:500 - 1:1000
IHC: 1:50 - 1:100 |
Positive Control 1 |
293T |
Positive Control 2 |
HeLa |
Positive Control 3 |
U-87MG,Jurkat |
Positive Control 4 |
Raji |
Positive Control 5 |
LO2 |
Predicted Molecular Weight |
Observed: 190kDa |
Purification |
Affinity purification |
Clonality |
Polyclonal |
Isotype |
IgG |
Conjugate |
Unconjugated |
Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage Conditions |
Store at -20˚ C. Avoid freeze / thaw cycles. |
Disclaimer |
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only. |
Modifications |
None |
Ncbi Official Symbol |
GIGYF2 |
Ncbi Gene Id # |
26058 |
User Note |
Optimal dilutions for each application to be determined by the researcher. |
Ncbi Official Symbol |
GIGYF2 |
Ncbi Official Full Name |
PERQ amino acid-rich with GYF domain-containing protein 2 |
Ncbi Organism |
Homo sapiens |
Swissprot # |
Q6Y7W6 |
Background |
This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants. |
1st Image Caption |
Western blot analysis of extracts of various cell lines, using GIGYF2 antibody (14-246) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.