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REL Antibody

REL Antibody

Item no.	PRS-14-150-50uL
Manufacturer	ProSci
Amount	50 uL
Category	Neuroscience Aging & Neurological Disorders Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB
Specific against	Human, Mouse, Rat
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	REL, C-Rel
Available
Shipping	blue ice or RT
By Research Area	Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction, Transcription
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human REL (NP_002899.1).
Applications	WB: 1:500 - 1:2000
Positive Control 1	HT-29
Positive Control 2	DU145
Positive Control 3	HL-60
Positive Control 4	Raji
Positive Control 5	Mouse heart
Positive Control 6	Mouse thymus
Predicted Molecular Weight	Observed: 68kDa
Purification	Affinity purification
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	REL
Ncbi Gene Id #	5966
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	REL
Ncbi Official Full Name	v-rel avian reticuloendotheliosis viral oncogene homolog
Ncbi Organism	Homo sapiens
Swissprot #	Q04864
Background	This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.
1st Image Caption	Western blot analysis of extracts of various cell lines, using REL antibody (14-150) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 uL

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Delivery expected until 9/6/2024

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