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CYP2E1 Antibody - N-terminal region (OABB01054)

CYP2E1 Antibody - N-terminal region (OABB01054)

Manufacturer	AVIVA Systems Biology
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	other
Isotype	IgG
Applications	WB
Amount	100 ug
Host	Rabbit
Item no.	OABB01054
eClass 6.1	32160702
eClass 9.0	32160702
Available
Gene symbol	CYP2E1
Product format	Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Gene id	1571
Reconstitution and storage	Add 0.2ml of distilled water will yield a concentration of 500ug/ml. Store at -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing.
Description of target	CYP2E1, also known as P450IIE1, is a member of the P450IIE subfamily which is ethanol-inducible. It has at least 1 gene which is mapped to 10q24.3-qter, and a second is likely in rat and in man. Both the rat and human proteins encoded by this gene contain 493 amino acids and calculated molecular masses of 56, 634 and 56, 916 daltons, respectively. In addition, genetic polymorphisms in the 5-prime flanking region of the human P450IIE1 gene affected its binding of transacting factor and changed its transcriptional regulation, which may lead to interindividual differences of microsomal drug oxidation activity. P450IIE1 is an important enzyme for the catalysis of the conversion of ethanol to acetaldehyde and to acetate in humans, and it is also involved in the metabolism of nitrosamines. Due to the possible correlation of P450IIE1 genes with malignancy, clinical studies of RFLP patterns of these genes in cancer may be useful.
Purification	Immunogen affinity purified.
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human Cytochrome P450 2E1(100-118aa RGDLPAFHAHRDRGIIFNN).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 100 ug

available

Delivery expected until 7/26/2024