Item no. |
NKM-ATGA0269-50ul |
Manufacturer |
NKMAX
|
Amount |
50ul |
Category |
|
Type |
Antibody Monoclonal |
Clone |
AT59D9 |
Specific against |
other |
Host |
Mouse |
Isotype |
IgG2b kappa |
Conjugate/Tag |
Unconjugated |
NCBI |
NP_056338 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Oligoribonuclease mitochondrial, Oligoribonuclease, mitochondrial, REX2, RNA exonuclease 2 homolog (S. cerevisiae), CGI-114, REX2, RFN, SFN |
Available |
|
Antigen Species |
Human |
Applications info |
ELISA, WB, ICC/IF |
Clonality Mono VS Poly |
Monoclonal |
Concentration |
1mg/ml |
Description |
REX2, RNA exonuclease 2 homolog (S. cerevisiae), also known as REXO2, is an enzyme which in humans is encoded by the REXO2 gene. Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair that also may be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mono-nucleotides in a sequential manner. |
Formulation |
Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. |
Gene Category |
Epigenomics (Transcription & Translation) |
General References |
Entrez Gene: REXO2 REX2, RNA exonuclease 2 homolog (S. cerevisiae) Lai, CH., et al. (2000) Genome Res 10(5): 703-13 Nguyen, LH., et al. (2000) J.Biol.Chem 275(34): 25900-6 |
Immunogen |
Recombinant human REXO 2 (26-237aa) purified from E. coli |
Reacts With |
Human |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Usage |
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.