Comparison

Human EIF2S1 antibody

Item no. NKM-ATGA0208-50ul
Manufacturer NKMAX
Amount 50ul
Category
Type Antibody Monoclonal
Clone AT5E10
Specific against other
Host Mouse
Isotype IgG2b kappa
Conjugate/Tag Unconjugated
NCBI NP_004085
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Eukaryotic translation initiation factor 2 subunit 1, EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A, Eukaryotic translation initiation factor 2 subunit 1 EIF 2 alpha, EIF 2, EIF 2A, EIF 2alpha, EIF2 alpha, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, Eukaryotic translation initiation factor 2 subunit 1 alpha, Eukaryotic translation initiation factor 2 subunit alpha.
Available
Antigen Species
Human
Applications info
ELISA, WB, ICC/IF
Clonality Mono VS Poly
Monoclonal
Concentration
1mg/ml
Description
Eukaryotic translation initiation factor 2, subunit 1 alpha (EIF2S1) is plays a central role in initiating translation, and provides for a rate-limiting step in protein synthesis. The phosphorylation of alpha-subunit of EIF2S1 effectively prevents formation of the EIF2S1/GTP/Met-tRNAi complex and inhibits global protein synthesis.
Formulation
Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Gene Category
Signal Transduction
General References
Kim JH, et al. (2011). EMBO J, 10
30(12):2454-64
Pena J, et al. (2011). J Biol Chem, 286(16):14226-36.
Muaddi H, et al. (2010). Mol Biol Cell, 21(18):3220-31
Immunogen
Recombinant human EIF2S1 (1-315aa) purified from E. coli
Reacts With
Human
Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Usage
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1, 000.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50ul
Available: In stock
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