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PLGF monoclonal antibody

PLGF monoclonal antibody

Manufacturer	Bioworld Technology, Inc
Category	Antibodies Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies
Type	Antibody Primary
Specific against	Human, Mouse, Rat
Applications	WB, IHC, ICC
Amount	50ul
Host	Mouse
Item no.	MB9434-50
Targets	PGF ;;VEGFA
eClass 6.1	32160702
eClass 9.0	32160702
Available
Alias	PlGF, PGF, PGFL, D12S1900, Pgf, PGFL, PIGF, Placenta growth factor, Placental growth factor, Placental growth factor, vascular endothelial growth factor related protein, PlGF 2, PlGF, PLGF, PlGF2, SHGC 10760,
Swiss-Prot	P49763(Human) P49764(Mouse) Q63434(Rat)
Application_all	WB:1:500 ICC:1:50 IHC:1:50-1:200
Background	The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF). Like VEGF, several PlGF variants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PlGF signaling. While VEGF homodimers and VEGF/PlGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PlGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PlGF. VEGF and PlGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.
Product	Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification And Purity	Protein affinity purified.
Storage And Stability	Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Specificity	PLGF monoclonal antibody detects endogenous levels of PLGF protein.
BiowMW	25 kDa
Note	For research use only, not for use in diagnostic procedure.
Immunogen	Recombinant protein within human PLGF 1-150 aa.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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