Item no. |
MB9384-50 |
Manufacturer |
Bioworld Technology, Inc
|
Amount |
50ul |
Category |
|
Type |
Antibody Primary |
Applications |
FC, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Mouse |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
NF1-B, Nuclear factor 1/B, CTF, NF-I/B, NFI-B, NFIB, CCAAT Box Binding Transcription Factor, CCAAT-box-binding transcription factor, CTF, HMGIC/NFIB, NF-I/B, NF1-B, NF1B, NF1B2, NFI-B, NFI-RED, Nfib, NFIB, NFIB2, NFIB3, Nuclear factor 1 B-type, Nuclear fa |
Available |
|
Swiss-Prot |
O00712(Human) P97863(Mouse) |
Application_all |
IHC:1:50-1:200 FC:1:50-1:100 |
Background |
NF-1, also designated CTF, consists of a family of CCAAT box binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA binding domain, and activates transcription through a putatively novel, proline-rich, carboxy terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, alpha-globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter. |
Product |
Mouse IgG2b, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
Purification And Purity |
Protein affinity purified. |
Storage And Stability |
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles. |
Specificity |
NFIB/NF1B2 monoclonal antibody detects endogenous levels of NFIB/NF1B2 protein. |
BiowMW |
47 kDa |
Note |
For research use only, not for use in diagnostic procedure. |
Immunogen |
Recombinant full length protein corresponding to human NFIB/NF1B2. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.