Antibody Details
Product Details
Reactivity Species
Human
Host Species
Rabbit
Product Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Storage and Handling
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Country of Origin
USA
RRID
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Description
Specificity
Rabbit Anti-Human Eotaxin recognizes an epitope near the C-terminus of Human Eotaxin. This polyclonal antibody was purified using affinity chromatography.
Background
The CC-chemokine eotaxin is a potent eosinophil chemoattractant that stimulates recruitment of eosinophils from the blood to sites of allergic inflammation.1 Eotaxin and related molecules are potentially important endogenous signaling substances in allergic reactions.2 Eotaxin plays an important role not only by attracting eosinophils to the site of inflammation but also by damaging tissue by its capacity to induce the release of reactive oxygen species.3
Antigen Details
Protein
Eotaxin
PubMed
Eotaxin
NCBI Gene Bank ID
6356
UniProt.org
More Information on Uniprot.org
References & Citations
1. Rankin SM. et al. (1998) Blood. 91:22402. Williams TJ. et al. (1993) Biochem Biophys Res Commun. 197:11673. Kapp A. et al. (1996) Eur J Immunol. 26:1919
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