Anti-Human Eotaxin (CT)

Antibody Details

Product Details

Reactivity Species

Human

Host Species

Rabbit

Product Concentration

0.5 mg/ml

Formulation

This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.

Storage and Handling

This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Country of Origin

USA

RRID

AB_2829996

Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

Description

Specificity

Rabbit Anti-Human Eotaxin recognizes an epitope near the C-terminus of Human Eotaxin. This polyclonal antibody was purified using affinity chromatography.

Background

The CC-chemokine eotaxin is a potent eosinophil chemoattractant that stimulates recruitment of eosinophils from the blood to sites of allergic inflammation.¹ Eotaxin and related molecules are potentially important endogenous signaling substances in allergic reactions.² Eotaxin plays an important role not only by attracting eosinophils to the site of inflammation but also by damaging tissue by its capacity to induce the release of reactive oxygen species.³

Antigen Details

Protein

Eotaxin

PubMed

Eotaxin

NCBI Gene Bank ID

6356

UniProt.org

More Information on Uniprot.org

References & Citations

1. Rankin SM. et al. (1998) Blood. 91:2240
2. Williams TJ. et al. (1993) Biochem Biophys Res Commun. 197:1167
3. Kapp A. et al. (1996) Eur J Immunol. 26:1919

Technical Protocols