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Sintilimab Biosimilar - Research Grade

Sintilimab Biosimilar - Research Grade

Item no.	ICH5001-1mg
Manufacturer	IchorBio
Amount	1 mg
Quantity options	100 mg 10 mg 1 mg 20 mg 50 mg 5 mg
Category	Antibodies In Vivo Antibodies
Type	Biosimilars
Applications	FA
Specific against	Human (Homo sapiens)
Host	Humanized
Isotype	IgG4
Purity	>95% by SDS-PAGE and HPLC
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Programmed cell death protein 1, Pdcd1, CD279
Shipping condition	Cool pack
Available
Specificity	Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Sintilimab.
Manufacturer - Applications	Functional Assays
Manufacturer - Category	Low endotoxin, Biosimilar, recombinant antibody
Manufacturer - Isotype	Human IgG4
Manufacturer - Targets	PD-1
Manufacturer - Host	Humanized
Shipping Temperature	Blue ice
Storage Conditions	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation	Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Application Notes	This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Background	Pembrolizumab biosimilar is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. It is an IgG4 kappa immunoglobulin with an approximate molecular weight of 149 kDa.
Concentration	1.0 - 5.0 mg/ml
Endotoxin	<1EU/mg Determined by LAL gel clotting assay
Manufacturer - Specificity	Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Sintilimab.
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control	Bulk Human IgG4 Isotype Control (IB4) [ICH2257]
Buffer	ICH3002

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 2/7/2025

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