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Vedolizumab Biosimilar - Research Grade

Vedolizumab Biosimilar - Research Grade

Item no.	ICH4035-5MG
Manufacturer	IchorBio
Amount	5mg
Category	Antibodies In Vivo Antibodies
Type	Biosimilars
Specific against	Human
Host	Humanized
Isotype	IgG1
Purity	>95% by SDS-PAGE and HPLC
Citations	Dipasquale et al. Biosimilars in Pediatric IBD: Updated Considerations for Disease Management Parrish II, RH. Biosimilar Interchangeability and Emerging Treatment Strategies for Inflammatory Bowel Diseases: A Commentary. Gastroenterology Insights
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ITGA4, ITGB7
Available
Specificity	Detects human Integrin α4β7. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Vedolizumab. This product is for research use only.
Manufacturers Product Category	Low endotoxin, biosimilar antibody
Target Information	Integrin alpha 4 + beta 7
Isotype Information	Human IgG1
Host Information	Humanized
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background	Vedolizumab, an integrin receptor antagonist, is a humanized IgG1 monoclonal antibody produced in Chinese hamster ovary cells that binds to the human α4β7 integrin. Vedolizumab has an approximate molecular weight of 147 kilodaltons.
Concentration	1.0 - 5.0 mg/ml
Formulation	Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Endotoxin	≤ 0.5 EU/mg as determined by the LAL method
Storage	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5mg

available

Delivery expected until 12/20/2024