Item no. |
ICH4032-5MG |
Manufacturer |
IchorBio
|
Amount |
5mg |
Category |
|
Type |
Biosimilars |
Specific against |
Human |
Host |
Humanized |
Isotype |
IgG1 |
Purity |
>95% by SDS-PAGE and HPLC |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Vascular endothelial growth factor receptor 2, Kdr, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase NYK, Protein-tyrosine kinase receptor flk-1, Flk1, CD309 |
Available |
|
Specificity |
Detects human VEGFR2. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Ramucirumab. This product is for research use only. |
Manufacturers Product Category |
Low endotoxin, biosimilar antibody |
Target Information |
VEGFR2 |
Isotype Information |
Human IgG1 |
Host Information |
Humanized |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Background |
Ramucirumab is a recombinant human IgG1 monoclonal antibody that specifically binds to vascular endothelial growth factor receptor 2. ramucirumab has an approximate molecular weight of 147 kDa. ramucirumab is produced in genetically engineered mammalian CHO cells. |
Concentration |
1.0 - 5.0 mg/ml |
Formulation |
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free. |
Endotoxin |
≤ 0.5 EU/mg as determined by the LAL method |
Storage |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.