Comparison

Ranibizumab Biosimilar - Research Grade European Partner

Item no. ICH4031-5MG
Manufacturer IchorBio
Amount 5mg
Category
Type Biosimilars
Specific against Human
Host Humanized
Isotype IgG1 Kappa
Purity >95% by SDS-PAGE and HPLC
Citations Gupta et al. Topical Delivery of Ranibizumab drops in Anti-aggregation diluent formula for retinal Delivery in Rabbits. ARVO Annual Meeting Abstract
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Vascular endothelial growth factor
Available
Specificity Detects human VEGF. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Ranibizumab. This product is for research use only.
Manufacturers Product Category
Low endotoxin, biosimilar antibody
Target Information
VEGF
Isotype Information
Human IgG1 Kappa
Host Information
Humanized
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment designed for intraocular use. Ranibizumab binds to and inhibits the biologic activity of human vascular endothelial growth factor A (VEGF-A). Ranibizumab, which lacks an Fc region, has a molecular weight of approximately 48 kilodaltons and is produced by CHO expression system.
Concentration
1.0 - 5.0 mg/ml
Formulation
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5mg
Available: In stock
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